SCHEMBL6338308

SCHEMBL6338308

COC(=O)c1ccccc1NC(=O)Cc1ccc(Oc2ccc(OC3CCC(N)CC3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 8/20 0.47
HSD17B10 Q99714 4/20 0.45
MAPK10 P53779 3/20 0.45
KDM4E B2RXH2 3/20 0.45
TSHR P16473 2/20 0.45
MEN1 O00255 1/20 0.44
MAPK8 P45983 1/20 0.44
MAPK9 P45984 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
HPGD P15428 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
POLB P06746 1/20 0.42
KCNQ2 O43526 1/20 0.42
TP53 P04637 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6338311 1.00 KMT2A (0.48) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL6347630 0.93 ALDH1A1 (0.44) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL6347628 0.93 ALDH1A1 (0.44) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL6348813 0.92 ALDH1A1 (0.43) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL6348815 0.92 ALDH1A1 (0.43) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL8037885 0.91 KMT2A (0.51) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL8037922 0.90 ALDH1A1 (0.50) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL8038289 0.90 ALDH1A1 (0.50) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL6406657 0.90 ALDH1A1 (0.50) KMT2AALDH1A1HSD17B10MAPK10KDM4E
SCHEMBL6339214 0.88 KMT2A (0.48) KMT2AALDH1A1HSD17B10MAPK10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 KMT2A 1762/4885ALDH1A1 250/4885HSD17B10 1100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.