Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628859 | 0.88 | MAOB (0.78) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL462351 | 0.88 | MAOB (0.78) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL27558493 | 0.85 | MAOB (0.74) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL30075910 | 0.85 | MAOB (0.74) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL27559747 | 0.82 | MAOB (0.61) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL15466749 | 0.82 | MAOB (0.61) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL11599873 | 0.82 | MAOB (0.61) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL15466750 | 0.82 | MAOB (0.61) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL11599869 | 0.82 | MAOB (0.61) | MAOBCA1CA2ARG2TOP1 | |
| Tert-Butanol SCHEMBL8960018 | 0.80 | MAOB (0.58) | MAOBCA1CA2ARG2TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6943224-B2 | Process for preparing supported transition metal catalyst systems and catalyst systems prepared thereby | W. R. GRACE & CO.-CONN. (US) | 2005-09-13 | — | — | US | disclosed |
| EP-1399491-A1 | SUPPORTED DUAL TRANSITION METAL CATALYST SYSTEMS | W.R. Grace & Co.-Conn. (US) | 2004-03-24 | — | — | EP | disclosed |
| US-20030224927-A1 | Process for preparing supported transition metal catalyst systems and catalyst systems prepared thereby | W. R. GRACE & CO.-CONN. | 2003-12-04 | — | — | US | disclosed |
| WO-2002088200-A1 | SUPPORTED DUAL TRANSITION METAL CATALYST SYSTEMS | W.R. GRACE & CO.-CONN. (US) | 2002-11-07 | — | — | WO | disclosed |