Tert-Butanol

Tert-Butanol

SCHEMBL8960018

C(C=CCc1ccccc1)=CCc1ccccc1.CC(C)(C)O

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.58
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ARG2 P78540 1/20 0.50
TOP1 P11387 1/20 0.42
SLC6A2 P23975 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2D6 P10635 2/20 0.38
CYP3A4 P08684 2/20 0.38
PRMT1 Q99873 1/20 0.38
LMNA P02545 1/20 0.38
TRPA1 O75762 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
KCNH2 Q12809 2/20 0.37
ALDH1A1 P00352 1/20 0.36
FDPS P14324 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL462351 0.86 MAOB (0.78) MAOBCA1CA2ARG2TOP1
SCHEMBL628859 0.86 MAOB (0.78) MAOBCA1CA2ARG2TOP1
SCHEMBL27558493 0.84 MAOB (0.74) MAOBCA1CA2ARG2TOP1
SCHEMBL30075910 0.84 MAOB (0.74) MAOBCA1CA2ARG2TOP1
SCHEMBL15466749 0.80 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL11599873 0.80 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL27559747 0.80 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL15466750 0.80 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL11599869 0.80 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL6339808 0.80 MAOB (0.61) MAOBCA1CA2ARG2TOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543480-A USING GROUP 4 METAL COMPLEXES CONTAINING A DIENE MOIETY THE DOW CHEMICAL COMPANY (US) 1996-08-06 US disclosed