Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | HBB | P68871 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | PNP | P00491 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.52 |
| ▸ | POLG | P54098 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507059 | 0.89 | MEN1 (0.75) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL29860149 | 0.87 | MEN1 (0.77) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL14986809 | 0.87 | MEN1 (0.77) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL12618101 | 0.86 | MEN1 (0.80) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL13928911 | 0.85 | MEN1 (0.65) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL4910722 | 0.85 | MEN1 (0.65) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL3702824 | 0.85 | MEN1 (0.49) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL712900 | 0.85 | MEN1 (0.49) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL712899 | 0.85 | MEN1 (0.49) | MEN1KMT2AHBBMAPK1PNP | |
| SCHEMBL3702827 | 0.85 | MEN1 (0.49) | MEN1KMT2AHBBMAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849737-B2 | Synthesis and purification of valacyclovir | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-02-01 | — | — | US | claimed |
| US-20030153757-A1 | Synthesis and purification of valacyclovir | TEVA PHARMACEUTICALS USA, INC. | 2003-08-14 | — | — | US | claimed |
| WO-2003041647-A2 | SYNTHESIS AND PURIFICATION OF VALACYCLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-05-22 | — | — | WO | claimed |
| US-10836765-B2 | Process for the preparation of valacyclovir | AUROBINDO PHARMA LTD (IN) | 2020-11-17 | — | — | US | disclosed |
| US-20190023706-A1 | Process for the preparation of Valacyclovir | AUROBINDO PHARMA LTD (IN) | 2019-01-24 | — | — | US | disclosed |
| CN-1307177-C | Synthesis and purification of valacyclovir | TEVA PHARMA (IL) | 2007-03-28 | — | — | CN | disclosed |
| CN-1896077-A | Synthesis and purification of valacyclovir | TEVA PHARMA (IL) | 2007-01-17 | — | — | CN | disclosed |
| US-20050130993-A1 | Synthesis and purification of valacyclovir | ETINGER MARINA Y (IL) | 2005-06-16 | — | — | US | disclosed |
| US-20050130993-A1 | Synthesis and purification of valacyclovir | ETINGER MARINA Y (IL) | 2005-06-16 | — | — | US | disclosed |
| CN-1612878-A | Synthesis and purification of valacyclovir | TEVA PHARMA (IL) | 2005-05-04 | — | — | CN | disclosed |
| US-6849737-B2 | Synthesis and purification of valacyclovir | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-02-01 | — | — | US | disclosed |
| US-6849737-B2 | Synthesis and purification of valacyclovir | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-02-01 | — | — | US | disclosed |
| WO-2003041647-A3 | SYNTHESIS AND PURIFICATION OF VALACYCLOVIR | TEVA PHARMA (IL) | 2003-11-20 | — | — | WO | disclosed |
| US-20030153757-A1 | Synthesis and purification of valacyclovir | TEVA PHARMACEUTICALS USA, INC. | 2003-08-14 | — | — | US | disclosed |
| US-20030153757-A1 | Synthesis and purification of valacyclovir | TEVA PHARMACEUTICALS USA, INC. | 2003-08-14 | — | — | US | disclosed |
| WO-2003041647-A2 | SYNTHESIS AND PURIFICATION OF VALACYCLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-05-22 | — | — | WO | disclosed |
| WO-2003041647-A2 | SYNTHESIS AND PURIFICATION OF VALACYCLOVIR | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130993-A1 | Synthesis and purification of valacyclovir | TYMP, TPMT, TYMS | MEN1 961/4885KMT2A 1354/4885HBB 1982/4885 |
| US-20030153757-A1 | Synthesis and purification of valacyclovir | TYMP, TPMT, TYMS | MEN1 828/4885KMT2A 1512/4885HBB 1907/4885 |
| US-20190023706-A1 | Process for the preparation of Valacyclovir | TYMP, SAMHD1, IMPDH1 | MEN1 975/4885KMT2A 1122/4885HBB 3666/4885 |
| US-10836765-B2 | Process for the preparation of valacyclovir | TYMP, SAMHD1, IMPDH1 | MEN1 975/4885KMT2A 1122/4885HBB 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.