Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.58 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.58 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343091 | 0.92 | ITGB1 (0.58) | ITGB1ITGA4ITGB7MMP1MMP2 | |
| SCHEMBL6344233 | 0.90 | ITGB1 (0.59) | ITGB1ITGA4ITGB7 | |
| SCHEMBL6792265 | 0.88 | ITGB1 (0.51) | ITGB1ITGA4ITGB7PLA2G1BATG4B | |
| SCHEMBL6354021 | 0.87 | PLA2G1B (0.59) | MMP1MMP2MMP3MMP9PLA2G1B | |
| SCHEMBL6346137 | 0.85 | FNTA (0.51) | ITGB1ITGA4ITGB7MMP1MMP2 | |
| SCHEMBL6343632 | 0.82 | ITGB1 (0.60) | ITGB1ITGA4ITGB7 | |
| SCHEMBL6354954 | 0.78 | NPC1 (0.49) | ITGB1ITGA4ITGB7MMP2MMP9 | |
| SCHEMBL6344213 | 0.78 | HPGD (0.55) | MMP1MMP2MMP3MMP9PLA2G1B | |
| SCHEMBL6353998 | 0.78 | ITGB1 (0.61) | ITGB1ITGA4ITGB7 | |
| SCHEMBL6344869 | 0.78 | MMP2 (0.54) | MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | claimed |