Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.54 |
| ▸ | CCR5 | P51681 | 17/20 | 0.45 |
| ▸ | CCR7 | P32248 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026555 | 0.97 | CCR2 (0.54) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL3040104 | 0.96 | CCR2 (0.54) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL6342614 | 0.96 | CCR2 (0.56) | CCR2CCR5CCR7 | |
| SCHEMBL6353159 | 0.95 | CCR2 (0.56) | CCR2CCR5CCR7 | |
| SCHEMBL3026515 | 0.93 | CCR2 (0.56) | CCR2CCR5CCR7 | |
| SCHEMBL6342915 | 0.92 | CCR2 (0.58) | CCR2CCR5CCR7 | |
| SCHEMBL6341617 | 0.90 | CCR2 (0.55) | CCR2CCR5CCR7 | |
| SCHEMBL6351792 | 0.90 | CCR2 (0.55) | CCR2CCR5CCR7 | |
| SCHEMBL6349067 | 0.90 | CCR2 (0.53) | CCR2CCR5CCR7 | |
| SCHEMBL6343597 | 0.89 | CCR2 (0.56) | CCR2CCR5CCR7CCR3CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |