SCHEMBL6341877

SCHEMBL6341877

C=CC(=O)NCCN(C)CCCC

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.61
ZDHHC2 Q9UIJ5 1/20 0.61
KDM4C Q9H3R0 8/20 0.41
KDM5A P29375 7/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 1/20 0.40
DNM1 Q05193 1/20 0.40
KDM4A O75164 2/20 0.40
PHF8 Q9UPP1 2/20 0.40
TP53 P04637 1/20 0.38
FAAH O00519 1/20 0.38
KDM5C P41229 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28063865 0.93 ZDHHC20 (0.67) ZDHHC20ZDHHC2KDM4CKDM5AALDH1A1
SCHEMBL511272 0.93 ZDHHC20 (0.66) ZDHHC20ZDHHC2KDM4CKDM5AALDH1A1
SCHEMBL17858061 0.91 ZDHHC20 (0.52) ZDHHC20ZDHHC2KDM5AALDH1A1TSHR
SCHEMBL5677655 0.89 ZDHHC20 (0.55) ZDHHC20ZDHHC2KDM4CKDM5AALDH1A1
SCHEMBL12301856 0.89 ZDHHC20 (0.52) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL19020248 0.88 ZDHHC20 (0.69) ZDHHC20ZDHHC2KDM4CKDM5AALDH1A1
SCHEMBL19020304 0.87 ZDHHC20 (0.72) ZDHHC20ZDHHC2KDM4CKDM5ADNM1
SCHEMBL15830118 0.86 ZDHHC20 (0.61) ZDHHC20ZDHHC2KDM4CKDM5AALDH1A1
SCHEMBL28516947 0.86 ZDHHC20 (0.55) ZDHHC20ZDHHC2KDM4CKDM5AALDH1A1
SCHEMBL12330583 0.85 ZDHHC20 (0.58) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050148748-A1 Copolymers and blood filter using the same TERUMO KABUSHIKI KAISHA (JP) 2005-07-07 US disclosed
US-20020000403-A1 Copolymers and blood filter using the same TERUMO KABUSHIKI KAISHA (JP) 2002-01-03 US disclosed
EP-1156067-A2 (Meth)Acrylic Copolymers comprising glycolether and aminoalkyl units and blood filter using the same TERUMO KABUSHIKI KAISHA (JP) 2001-11-21 EP disclosed