Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.47 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.47 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351819 | 0.87 | GFER (0.49) | GFERMAPTGAAKCNJ6KCNJ5 | |
| SCHEMBL6343958 | 0.83 | GFER (0.73) | GFERMAPTGAAKCNJ6KCNJ5 | |
| SCHEMBL6341582 | 0.81 | KMT2A (0.56) | GFERMAPTGAAKCNJ6KCNJ5 | |
| SCHEMBL6341149 | 0.80 | GFER (0.46) | GFERMAPTGAAKCNJ6KCNJ5 | |
| SCHEMBL17610516 | 0.78 | GFER (0.62) | GFERMAPTGAAKCNJ6KCNJ5 | |
| SCHEMBL5008346 | 0.75 | GFER (0.80) | GFERMAPTGAAKCNJ6KCNJ5 | |
| SCHEMBL14600238 | 0.73 | MAPK14 (0.53) | GAA | |
| SCHEMBL6342656 | 0.73 | KMT2A (0.53) | GFERMAPTGAANTRK1HPGD | |
| SCHEMBL6344753 | 0.73 | KMT2A (0.53) | GFERMAPTGAANTRK1HPGD | |
| SCHEMBL14600237 | 0.73 | MAPK14 (0.55) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949648-B2 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1270572-A1 | CONDENSED PYRAZOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187014-A1 | Condensed pyrazole derivatives, process for producing the same and use thereof | PTGS1, PTGIS, IL5 | GFER 2957/4885MAPT 3408/4885GAA 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.