Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6338918 | 0.98 | PTGER4 (0.54) | PTGER4PTGER3 | |
| SCHEMBL6338915 | 0.98 | PTGER4 (0.54) | PTGER4PTGER3 | |
| SCHEMBL6339162 | 0.93 | PTGER4 (0.51) | PTGER4PTGER3 | |
| SCHEMBL6338194 | 0.92 | PTGER4 (0.52) | PTGER4PTGER3 | |
| SCHEMBL6341389 | 0.91 | PTGER4 (0.48) | PTGER4PTGER3 | |
| SCHEMBL6341221 | 0.89 | PTGER4 (0.46) | PTGER4PTGER3 | |
| SCHEMBL6341549 | 0.89 | PTGER4 (0.50) | PTGER4PTGER3 | |
| SCHEMBL6337238 | 0.88 | PTGER4 (0.49) | PTGER4PTGER3 | |
| SCHEMBL6347395 | 0.87 | PTGER4 (0.51) | PTGER4PTGER3 | |
| SCHEMBL6337239 | 0.87 | PTGER4 (0.48) | PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835752-B2 | Can bind to Prostaglandin E2 receptors, especially, EP3 receptor and/or EP4 receptor and show antagonizing activity, and may be useful for prevention and/or treatment of disease, for example, pain, allergy, Alzheimer's disease, cancer | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-28 | — | — | US | claimed |
| US-20030216381-A1 | Carboxylic acid derivatives, process for producing the same and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| EP-1312601-A1 | CARBOXYLIC ACID DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-21 | — | — | EP | claimed |
| US-20050026908-A1 | Carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical aggents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2005-02-03 | — | — | US | disclosed |
| US-6835752-B2 | Can bind to Prostaglandin E2 receptors, especially, EP3 receptor and/or EP4 receptor and show antagonizing activity, and may be useful for prevention and/or treatment of disease, for example, pain, allergy, Alzheimer's disease, cancer | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-28 | — | — | US | disclosed |
| US-20040235825-A1 | Carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2004-11-25 | — | — | US | disclosed |
| US-20030216381-A1 | Carboxylic acid derivatives, process for producing the same and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1312601-A1 | CARBOXYLIC ACID DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026908-A1 | Carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical aggents comprising the same as active ingredient | PTGER4, PTGER3, LTB4R | PTGER4 1/4885PTGER3 2/4885 |
| US-20040235825-A1 | Carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | PTGER4, PTGER1, LTB4R | PTGER4 1/4885PTGER3 8/4885 |
| US-20030216381-A1 | Carboxylic acid derivatives, process for producing the same and drugs containing the same as the active ingredient | PTGER4, PTGER1, PTGER2 | PTGER4 1/4885PTGER3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.