SCHEMBL63427

SCHEMBL63427

COc1cccc(C(=O)O)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.74
CES1 P23141 1/20 0.74
PARP1 P09874 1/20 0.69
RAB9A P51151 5/20 0.68
NPC1 O15118 4/20 0.68
MITF O75030 1/20 0.68
MRGPRX4 Q96LA9 2/20 0.66
AKR1C3 P42330 1/20 0.66
KDM4E B2RXH2 1/20 0.63
SMN1; SMN2 Q16637 2/20 0.62
KMT2A Q03164 2/20 0.61
CYP2C8 P10632 1/20 0.60
MEN1 O00255 1/20 0.59
KCNK3 O14649 1/20 0.58
KCNK9 Q9NPC2 1/20 0.58
TP53 P04637 1/20 0.58
PKM P14618 1/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351426 1.00 CES2 (0.74) CES2CES1PARP1RAB9ANPC1
SCHEMBL6827745 1.00 CES2 (0.74) CES2CES1PARP1RAB9ANPC1
SCHEMBL10403563 0.98 CES2 (0.71) CES2CES1PARP1RAB9ANPC1
Water SCHEMBL27893543 0.98 CES2 (0.71) CES2CES1PARP1RAB9ANPC1
Hydrochloric Acid SCHEMBL30142542 0.98 CES2 (0.71) CES2CES1PARP1RAB9ANPC1
Hydrochloric Acid SCHEMBL5773812 0.98 CES2 (0.71) CES2CES1PARP1RAB9ANPC1
SCHEMBL1448094 0.98 CES2 (0.71) CES2CES1PARP1RAB9ANPC1
Acetic Acid SCHEMBL6440401 0.96 CES2 (0.69) CES2CES1PARP1RAB9ANPC1
Formaldehyde SCHEMBL11142552 0.96 CES2 (0.69) CES2CES1PARP1RAB9ANPC1
Carbamic Acid SCHEMBL2146141 0.93 PARP1 (0.71) CES2CES1PARP1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3182 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545794-B2 Security feature, printing ink, document of value, and manufacturing method GIESECKE+DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) 2026-02-10 US claimed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-3946240-B1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO KGAA (DE) 2025-10-15 EP claimed
CN-119969399-A Use of Feng Zhi element or analogues thereof as plant growth regulators 东北农业大学 2025-05-13 CN claimed
CN-119859148-A Spiroteine framework compound and preparation method and application thereof 安徽农业大学 2025-04-22 CN claimed
CN-119638770-A Clobetasol propionate derivative and preparation method thereof 复旦大学 2025-03-18 CN claimed
CN-118027834-B Ultraviolet-resistant card protection film and preparation process thereof 惠州艺都文化用品有限公司 2025-03-07 CN claimed
CN-119504479-A Capsaicin ester derivative, preparation method and application thereof 西北农林科技大学 2025-02-25 CN claimed
CN-119431432-A Andrographolide diester derivative, preparation method and application 西北农林科技大学 2025-02-14 CN claimed
US-20250018739-A1 SECURITY FEATURE, PRINTING INK, DOCUMENT OF VALUE, AND MANUFACTURING METHOD GIESECKE+DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) 2025-01-16 US claimed
US-5117002-A PREPARATION OF DIPHENYL ETHER OCCIDENTAL CHEMICAL CORPORATION (US) 1992-05-26 US claimed
EP-0067770-B1 TREATMENT OF MIGRAINE WITH TROPYL BENZOATE DERIVATIVES MERRELL DOW FRANCE ET CIE (FR) 1992-01-15 EP claimed
US-4982005-A BORON TRIFLUORIDE CATALYST BASF AKTIENGESELLSCHAFT (DE) 1991-01-01 US claimed
EP-0214158-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1987-03-18 EP claimed
WO-1986004582-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1986-08-14 WO claimed
EP-0031561-B1 A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT MERCK & CO. INC. (US) 1985-04-10 EP claimed
US-4394291-A COORDINATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1983-07-19 US claimed
EP-0060443-A1 Catalyst and use of same for polymerization PHILLIPS PETROLEUM COMPANY (US) 1982-09-22 EP claimed
US-4332962-A RHODIUM COMPOUND AS CATALYST FOR CYCLIZATION OF A PENTADIENE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-06-01 US claimed
US-3963787-A PALLADIUM CARBOXYLATE CATALYST TEIJIN LIMITED (JA) 1976-06-15 US claimed