Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031940 | 0.97 | — | — | |
| SCHEMBL12094462 | 0.92 | — | — | |
| SCHEMBL19539461 | 0.86 | — | — | |
| SCHEMBL9971146 | 0.77 | SHBG (0.43) | SHBGEPHX1CYP1A2 | |
| SCHEMBL16026654 | 0.75 | SHBG (0.41) | SHBGEPHX1CYP1A2 | |
| SCHEMBL19953936 | 0.74 | EPHX1 (0.56) | SHBGEPHX1TP53KDM4EGMNN | |
| SCHEMBL8153354 | 0.74 | EPHX1 (0.39) | SHBGEPHX1TP53KDM4EGMNN | |
| SCHEMBL28566559 | 0.73 | SHBG (0.40) | SHBGEPHX1CYP1A2 | |
| SCHEMBL4358257 | 0.72 | SHBG (0.62) | SHBGEPHX1TP53KDM4EGMNN | |
| SCHEMBL5400953 | 0.72 | SHBG (0.62) | SHBGEPHX1TP53KDM4EGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190791-A1 | INHIBITING CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB) | FORMA THERAPEUTICS, INC. (US) | 2020-09-24 | — | — | WO | disclosed |
| EP-2419400-A1 | MONOAMINE REUPTAKE INHIBITORS | RESEARCH TRIANGLE INSTITUTE (US) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010121022-A1 | MONOAMINE REUPTAKE INHIBITORS | RESEARCH TRIANGLE INSTITUTE (US) | 2010-10-21 | — | — | WO | disclosed |