Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutane SCHEMBL28089335 | 0.84 | CRBN (0.56) | CRBNTDP1LMNATSHRNFKB1 | |
| SCHEMBL17220675 | 0.77 | — | — | |
| SCHEMBL27939070 | 0.77 | CRBN (0.60) | CRBNTDP1LMNATSHRNFKB1 | |
| SCHEMBL27560286 | 0.77 | CRBN (0.60) | CRBNTDP1LMNATSHRNFKB1 | |
| SCHEMBL27524722 | 0.77 | CRBN (0.60) | CRBNTDP1LMNATSHRNFKB1 | |
| SCHEMBL15045 | 0.77 | — | — | |
| Acetone SCHEMBL29173292 | 0.74 | TDP1 (0.61) | TDP1LMNATSHRNFKB1BLM | |
| SCHEMBL11354262 | 0.74 | CRBN (0.50) | CRBNTDP1LMNATSHRNFKB1 | |
| Cyclopentane SCHEMBL22729196 | 0.74 | CRBN (0.50) | CRBNTDP1LMNATSHRNFKB1 | |
| Cyclohexane SCHEMBL1882975 | 0.74 | CRBN (0.50) | CRBNTDP1LMNATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100344669-C | Set-stable blocked polyisocyanates | BAYER MATERIALSCIENCE AG (DE) | 2007-10-24 | — | — | CN | disclosed |
| CN-1791625-A | Set-stable blocked polyisocyanates | BAYER MATERIALSCIENCE AG (DE) | 2006-06-21 | — | — | CN | disclosed |
| US-20050070683-A1 | Solidification-stable blocked polyisocyanates | BAYER MATERIALSCIENCE AG (DE) | 2005-03-31 | — | — | US | disclosed |