Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.51 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346179 | 0.89 | ITGB3 (0.50) | POLBITGB3ITGA2BITGA2SMN1; SMN2 | |
| SCHEMBL6344072 | 0.88 | POLB (0.51) | POLBITGB3ITGA2BSMN1; SMN2ITGB1 | |
| SCHEMBL6788398 | 0.88 | POLB (0.51) | POLBITGB3ITGA2BITGA2SMN1; SMN2 | |
| SCHEMBL6343632 | 0.86 | ITGB1 (0.60) | POLBITGB3ITGA2BSMN1; SMN2ITGB1 | |
| SCHEMBL6345390 | 0.84 | POLB (0.51) | POLBITGB3ITGA2BSMN1; SMN2ITGB1 | |
| SCHEMBL6342636 | 0.84 | POLB (0.47) | POLBITGB3ITGA2BITGA2SMN1; SMN2 | |
| Toluene SCHEMBL6343073 | 0.84 | POLB (0.47) | POLBITGB3ITGA2BITGA2SMN1; SMN2 | |
| SCHEMBL6354846 | 0.84 | ITGB1 (0.49) | POLBITGB3ITGA2BSMN1; SMN2ITGB1 | |
| SCHEMBL6342634 | 0.84 | POLB (0.47) | POLBITGB3ITGA2BITGA2SMN1; SMN2 | |
| SCHEMBL6346378 | 0.84 | POLB (0.51) | POLBITGB3ITGA2BITGA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | claimed |