Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441359 | 0.94 | HPGD (0.53) | HPGDEPHX2CYP2D6CYP2C19MMP1 | |
| SCHEMBL11798160 | 0.92 | HPGD (0.51) | HPGDEPHX2CYP2D6CYP2C19EPHX1 | |
| Water SCHEMBL10443430 | 0.92 | HPGD (0.51) | HPGDEPHX2CYP2D6CYP2C19MMP1 | |
| SCHEMBL2623081 | 0.86 | CYP2D6 (0.52) | HPGDEPHX2CYP2D6CYP2C19MMP1 | |
| SCHEMBL11519349 | 0.85 | ALDH1A1 (0.45) | HPGDEPHX2RECQLPTPN1 | |
| SCHEMBL16625022 | 0.83 | HPGD (0.54) | HPGDEPHX2CYP2D6CYP2C19MMP1 | |
| SCHEMBL9570167 | 0.83 | HPGD (0.54) | HPGDEPHX2CYP2D6CYP2C19MMP1 | |
| SCHEMBL3914202 | 0.83 | HPGD (0.54) | HPGDEPHX2CYP2D6CYP2C19EPHX1 | |
| SCHEMBL11043388 | 0.82 | EPHX2 (0.41) | HPGDEPHX2SMN1; SMN2PTPN1 | |
| SCHEMBL28425942 | 0.81 | HPGD (0.57) | HPGDEPHX2CYP2D6CYP2C19MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183307-B2 | Pyrazole-derived kinase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCROPORATED (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183307-B2 | Pyrazole-derived kinase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCROPORATED (US) | 2007-02-27 | — | — | US | disclosed |
| US-6894007-B2 | Additives for inhibiting gas hydrate formation | CLARIANT GMBH (DE) | 2005-05-17 | — | — | US | disclosed |
| US-20030013614-A1 | Additives for inhibiting gas hydrate formation | CLARIANT GMBH | 2003-01-16 | — | — | US | disclosed |
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |