Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 3/20 | 0.52 |
| ▸ | FGF2 | P09038 | 2/20 | 0.52 |
| ▸ | HPSE | Q9Y251 | 9/20 | 0.38 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064312 | 1.00 | FGF1 (0.52) | FGF1FGF2HPSESERPINC1SMPD1 | |
| SCHEMBL8781188 | 1.00 | FGF1 (0.52) | FGF1FGF2HPSESERPINC1SMPD1 | |
| SCHEMBL2507111 | 0.98 | FGF1 (0.51) | FGF1FGF2HPSESERPINC1SMPD1 | |
| SCHEMBL5178539 | 0.88 | FGF1 (0.42) | FGF1FGF2SERPINC1SMPD1F10 | |
| SCHEMBL8781311 | 0.88 | FGF1 (0.42) | FGF1FGF2SERPINC1SMPD1F10 | |
| SCHEMBL3700622 | 0.85 | FGF1 (0.59) | FGF1FGF2HPSESERPINC1 | |
| SCHEMBL3944961 | 0.85 | FGF1 (0.42) | FGF1FGF2SERPINC1SMPD1F10 | |
| SCHEMBL6675901 | 0.85 | FGF1 (0.42) | FGF1FGF2SERPINC1SMPD1F10 | |
| SCHEMBL29535174 | 0.84 | FGF1 (0.45) | FGF1FGF2HPSESERPINC1SMPD1 | |
| SCHEMBL29535822 | 0.84 | FGF1 (0.45) | FGF1FGF2HPSESERPINC1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939570-B1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON (US) | 2005-09-06 | — | — | US | disclosed |