Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19020347 | 1.00 | IDO1 (0.38) | IDO1SMN1; SMN2TP53HDAC4HDAC2 | |
| SCHEMBL8665494 | 0.93 | — | — | |
| SCHEMBL5473618 | 0.81 | IDO1 (0.37) | IDO1SMN1; SMN2TP53HDAC4HDAC2 | |
| SCHEMBL27610746 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL4109918 | 0.81 | IDO1 (0.37) | IDO1SMN1; SMN2TP53HDAC4HDAC2 | |
| SCHEMBL27480405 | 0.80 | HDAC4 (0.32) | IDO1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL10338316 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2TRPV3 | |
| SCHEMBL10338313 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2TRPV3 | |
| SCHEMBL21662744 | 0.79 | IDO1 (0.36) | IDO1TP53HIF1A | |
| SCHEMBL25717170 | 0.79 | IDO1 (0.36) | IDO1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397336-A4 | PREPARATION OF POLYARYL CARBOXYLIC ACIDS | HONEYWELL INT INC (US) | 2005-12-21 | — | — | EP | disclosed |
| US-20050065369-A1 | Preparation of polyaryl carboxylic acids | HONEYWELL INTERNATIONAL INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1397336-A2 | PREPARATION OF POLYARYL CARBOXYLIC ACIDS | Honeywell International Inc. (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002076382-A2 | PREPARATION OF POLYARYL CARBOXYLIC ACIDS | HONEYWELL INTERNATIONAL, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065369-A1 | Preparation of polyaryl carboxylic acids | PAH, TBCA, GABRA6 | IDO1 3977/4885SMN1; SMN2 3324/4885TP53 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.