Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328264 | 1.00 | ADORA2A (0.57) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6328271 | 1.00 | ADORA2A (0.57) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6345875 | 1.00 | ADORA2A (0.57) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6322425 | 0.89 | ADORA2A (0.62) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6322416 | 0.89 | ADORA2A (0.62) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6328212 | 0.84 | ADORA2A (0.45) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6321587 | 0.84 | ADORA2A (0.45) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6319299 | 0.79 | ADORA2A (0.42) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6319293 | 0.79 | ADORA2A (0.42) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4376279 | 0.78 | ADORA2A (0.55) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900309-B1 | Purine derivatives | PFIZER INC (US) | 2005-05-31 | — | — | US | disclosed |