Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL5861342 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL6046507 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL276158 | 1.00 | ALDH1A1 (0.74) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL11579143 | 0.97 | ALDH1A1 (0.70) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL6252701 | 0.97 | ALDH1A1 (0.70) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL882 | 0.97 | ALDH1A1 (0.70) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL3507062 | 0.97 | ALDH1A1 (0.70) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL11069490 | 0.95 | ALDH1A1 (0.67) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL1399223 | 0.95 | ALDH1A1 (0.67) | ALDH1A1LMNAHSD17B10TSHRTRPA1 | |
| Ethyl Acetate SCHEMBL1552436 | 0.95 | ALDH1A1 (0.67) | ALDH1A1LMNAHSD17B10TSHRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187279-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBVIE INC. | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187279-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | ALDH1A1 2303/4885LMNA 3740/4885HSD17B10 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.