Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.55 |
| ▸ | RXRB | P28702 | 14/20 | 0.55 |
| ▸ | RXRG | P48443 | 12/20 | 0.55 |
| ▸ | RARB | P10826 | 7/20 | 0.55 |
| ▸ | RARG | P13631 | 7/20 | 0.55 |
| ▸ | RARA | P10276 | 5/20 | 0.55 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | BLVRB | P30043 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344748 | 1.00 | RXRA (0.55) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6343496 | 1.00 | RXRA (0.55) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6335047 | 0.99 | RXRA (0.56) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6342047 | 0.96 | RXRA (0.57) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL3934850 | 0.93 | RARB (0.58) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL3938335 | 0.91 | RARB (0.56) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6337770 | 0.89 | SMN1; SMN2 (0.46) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6343404 | 0.87 | SMN1; SMN2 (0.47) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL3931644 | 0.87 | RARB (0.56) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL3933986 | 0.85 | RXRA (0.56) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844466-B2 | Alkyl urea retinoid agonists | SYNTEX (U.S.A.) LLC (US) | 2005-01-18 | — | — | US | disclosed |
| EP-1430024-A1 | ALKYL UREA RETINOID AGONISTS I | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-23 | — | — | EP | disclosed |
| US-20030158226-A1 | Alkyl urea retinoid agonists | ROCHE BIOSCIENCE, A DIVISION OF SYNTEX (U.S.A.) LLC | 2003-08-21 | — | — | US | disclosed |
| WO-2003024921-A1 | ALKYL UREA RETINOID AGONISTS I | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158226-A1 | Alkyl urea retinoid agonists | RXRG, RXRA, RXRB | RXRA 2/4885RXRB 3/4885RXRG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.