Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25279157 | 0.95 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL10905754 | 0.94 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL30038460 | 0.93 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL20261906 | 0.93 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL28195407 | 0.88 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Hexane SCHEMBL28069832 | 0.87 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1331857 | 0.87 | — | — | |
| SCHEMBL5681395 | 0.87 | TSHR (1.00) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL15037 | 0.87 | — | — | |
| SCHEMBL1330627 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10875282-B2 | Shape memory assisted self-healing polymers having load bearing structure | SYRACUSE UNIVERSITY (US) | 2020-12-29 | — | — | US | claimed |
| US-10368993-B2 | Shape-memory-actuated materials for accelerated healing of orthopedic injuries | SYRACUSE UNIVERSITY (US) | 2019-08-06 | — | — | US | claimed |
| US-10181381-B2 | Tunable shape memory capacitor and a method of preparation thereof | KING ABDULAZIZ UNIVERSITY (SA) | 2019-01-15 | — | — | US | claimed |
| US-20180053603-A1 | TUNABLE SHAPE MEMORY CAPACITOR AND A METHOD OF PREPARATION THEREOF | KING ABDULAZIZ UNIVERSITY (SA) | 2018-02-22 | — | — | US | claimed |
| US-20170312082-A1 | SHAPE-MEMORY-ACTUATED MATERIALS FOR ACCELERATED HEALING OF ORTHOPEDIC INJURIES | SYRACUSE UNIVERSITY (US) | 2017-11-02 | — | — | US | claimed |
| US-9744041-B2 | Shape-memory-actuated materials for accelerated healing of orthopedic injuries | SYRACUSE UNIVERSITY (US) | 2017-08-29 | — | — | US | claimed |
| US-20160135955-A1 | SHAPE-MEMORY-ACTUATED MATERIALS FOR ACCELERATED HEALING OF ORTHOPEDIC INJURIES | SYRACUSE UNIVERSITY (US) | 2016-05-19 | — | — | US | claimed |
| US-20150343749-A1 | Shape Memory Assisted Self-Healing Polymers Having Load Bearing Structure | SYRACUSE UNIVERSITY (US) | 2015-12-03 | — | — | US | claimed |
| WO-2014205306-A1 | SHAPE-MEMORY-ACTUATED MATERIALS FOR ACCELERATED HEALING OF ORTHOPEDIC INJURIES | SYRACUSE UNIVERSITY (US) | 2014-12-24 | — | — | WO | claimed |
| WO-2014113432-A1 | SHAPE MEMORY ASSISTED SELF-HEALING POLYMERS HAVING LOAD BEARING STRUCTURE | SYRACUSE UNIVERSITY (US) | 2014-07-24 | — | — | WO | claimed |
| US-20050238594-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers | L'OREAL S.A. (FR) | 2005-10-27 | — | — | US | claimed |
| US-10181381-B2 | Tunable shape memory capacitor and a method of preparation thereof | KING ABDULAZIZ UNIVERSITY (SA) | 2019-01-15 | — | — | US | disclosed |
| US-20180053603-A1 | TUNABLE SHAPE MEMORY CAPACITOR AND A METHOD OF PREPARATION THEREOF | KING ABDULAZIZ UNIVERSITY (SA) | 2018-02-22 | — | — | US | disclosed |
| US-4900655-A | CONTAINING SPECIFIC MAGENTA COUPLER AND HIGH BOILING SOLVENT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050238594-A1 | Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers | KRT18, DSG1, VCL | TSHR 3721/4885HPGD 518/4885ALDH1A1 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.