Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6350887 | 1.00 | PDE4D (0.42) | PDE4DASAH1MAPTTP53CYP1A2 | |
| SCHEMBL6350880 | 1.00 | PDE4D (0.42) | PDE4DASAH1MAPTTP53CYP1A2 | |
| SCHEMBL29259205 | 0.88 | MEN1 (0.50) | PDE4DMAPTTP53CYP1A2CYP2D6 | |
| SCHEMBL500452 | 0.85 | MEN1 (0.46) | PDE4DMAPTTP53CYP1A2CYP2D6 | |
| SCHEMBL500451 | 0.85 | MEN1 (0.46) | PDE4DMAPTTP53CYP1A2CYP2D6 | |
| SCHEMBL6354840 | 0.82 | EPHX2 (0.49) | PDE4DMAPTTP53CYP1A2CYP2D6 | |
| SCHEMBL6354839 | 0.82 | EPHX2 (0.49) | PDE4DMAPTTP53CYP1A2CYP2D6 | |
| SCHEMBL6137635 | 0.82 | EPHX2 (0.49) | PDE4DMAPTTP53CYP1A2CYP2D6 | |
| SCHEMBL30368256 | 0.82 | GALR3 (0.47) | PDE4DMEN1KMT2AGALR3 | |
| SCHEMBL29094957 | 0.82 | MEN1 (0.45) | PDE4DMAPTTP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020680-A1 | Hydroxyfattysulfonic acid analogs | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020680-A1 | Hydroxyfattysulfonic acid analogs | ELANE, HRH2, APEH | PDE4D 4214/4885ASAH1 77/4885MAPT 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.