SCHEMBL635089

SCHEMBL635089

Cc1cccc(C)c1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
TSHR P16473 6/20 0.75
SMN1; SMN2 Q16637 2/20 0.58
HSD17B10 Q99714 1/20 0.56
KAT2B Q92831 1/20 0.50
CYP3A4 P08684 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.47
ACHE P22303 1/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
GPR35 Q9HC97 1/20 0.45
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28521563 0.97 ALDH1A1 (0.95) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL27930239 0.89 ALDH1A1 (0.79) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL28375216 0.89 ALDH1A1 (0.79) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL11847292 0.88 ALDH1A1 (0.78) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL1101208 0.86 TSHR (1.00) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL29359563 0.86 TSHR (1.00) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL146895 0.86 TSHR (1.00) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL11339777 0.86 ALDH1A1 (0.75) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL8957021 0.85 ALDH1A1 (0.73) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10
SCHEMBL23874398 0.84 ALDH1A1 (0.72) ALDH1A1TDP1TSHRSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 764 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12508318-B2 UV light-responsive hyperbranched poly-β-amino ester having high-efficiency gene delivery ability and preparation method and application thereof SOOCHOW UNIVERSITY (CN) 2025-12-30 US claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-119431153-A Method for continuously preparing 2, 6-dimethylaniline 台州普渡机械设备有限公司 2025-02-14 CN claimed
US-20240415115-A1 ANTIMICROBIAL PHOTOACTIVE NANOFIBROUS POLYMER MATERIAL LAM-X a.s. (CZ) 2024-12-19 US claimed
EP-4432833-A1 ANTIMICROBIAL PHOTOACTIVE NANOFIBROUS POLYMER MATERIAL LAM-X a.s. (CZ) 2024-09-25 EP claimed
US-12087931-B2 Hybrid battery system with multiple discharge voltage plateaus and greater charge capacity of metal in the negative electrode CNPC USA CORPORATION (US) 2024-09-10 US claimed
CN-118149966-A Micro-size coaxial power sensor and implementation method thereof 中国计量科学研究院 2024-06-07 CN claimed
US-20240141759-A1 METHOD FOR POWERING WITH A HYBRID BATTERY PACK SYSTEM CNPC USA CORPORATION 2024-05-02 US claimed
CN-116693433-B Synthesis method of alkyl substituted thiophenol 济南悟通生物科技有限公司 2024-04-16 CN claimed
CN-114748420-B Preparation method of amphiphilic polymer micelle with charge self-overturning activation mitochondrial targeting effect 武汉科技大学 2024-03-08 CN claimed
CN-1022483-C Process for preparing 2, 4-dimethylaniline and 2, 6-dimethylaniline ZHEJIANG POLYTECHNIC COLLEGE (CN) 1993-10-20 CN claimed
CN-1055922-A 2,4-xylidine and 2, the preparation method of 6-xylidine ZHEJIANG POLYTECHNIC COLLEGE (CN) 1991-11-06 CN claimed
EP-0385441-A1 Marker for petroliferous products ACNA CHIMICA ORGANICA S.P.A. (IT) 1990-09-05 EP claimed
EP-0150169-B1 A PROCESS FOR PREPARING SUBSTITUTED BENZOTRICHLORIDE COMPOUNDS Monsanto Company (US) 1987-11-11 EP claimed
EP-0085511-B1 PROCESS FOR PREPARING P-AMINOPHENOL AND ALKYL SUBSTITUTED P-AMINOPHENOL MALLINCKRODT, INC.(a Missouri corporation) (US) 1986-03-12 EP claimed
US-4571437-A CATALYTIC HYDROGENATION REDUCTION AND REARRANGEMENT OF NITROBENZENE IN PRESENCE OF SULFUR COMPOUND MALLINCKRODT, INC. (US) 1986-02-18 US claimed
US-4549938-A Separation of methanol from methyl acetate by extractive distillation BERG LLOYD 1985-10-29 US claimed
EP-0086363-B1 PROCESS FOR THE PREPARATION OF ARYLHYDROXYLAMINES MALLINCKRODT, INC.(a Missouri corporation) (US) 1985-04-24 EP claimed
EP-0086363-A1 Process for the preparation of arylhydroxylamines MALLINCKRODT, INC.(a Missouri corporation) (US) 1983-08-24 EP claimed
US-4137254-A Preparation of aromatic nitriles TEXACO, INC. (US) 1979-01-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12508318-B2 UV light-responsive hyperbranched poly-β-amino ester having high-efficiency gene delivery ability and preparation method and application thereof ERCC2, MYD88, SLC7A1 ALDH1A1 938/4885TDP1 1165/4885TSHR 2900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.