SCHEMBL635167

SCHEMBL635167

C=CC(=O)OCCN(C)C.C=Cc1ccncc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.51
CHRM2 P08172 4/20 0.48
CHRM4 P08173 4/20 0.48
CHRM5 P08912 4/20 0.48
CHRM1 P11229 4/20 0.48
CHRM3 P20309 4/20 0.48
THRB P10828 1/20 0.39
PHLPP2 Q6ZVD8 1/20 0.38
TSHR P16473 5/20 0.38
HPGD P15428 1/20 0.38
SNCA P37840 1/20 0.38
ALDH1A1 P00352 5/20 0.38
TP53 P04637 2/20 0.38
HIF1A Q16665 2/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL446572 0.86 THRB (0.51) BCHECHRM2CHRM4CHRM5CHRM1
SCHEMBL9776540 0.85 BCHE (0.50) BCHECHRM2CHRM4CHRM5CHRM1
Styrene SCHEMBL27559766 0.83 THRB (0.49) BCHECHRM2CHRM4CHRM5CHRM1
SCHEMBL15638611 0.82 TSHR (0.63) THRBTSHRHPGDSNCAALDH1A1
Acrylic Acid Ethyl Ester SCHEMBL15638532 0.81 SNCA (0.42) THRBTSHRHPGDSNCAALDH1A1
SCHEMBL15115 0.80 TSHR (0.56) BCHECHRM2CHRM4CHRM5CHRM1
Styrene SCHEMBL9249860 0.79 THRB (0.45) BCHECHRM2CHRM4CHRM5CHRM1
Ethylene SCHEMBL8397415 0.78 TSHR (0.54) BCHECHRM2CHRM4CHRM5CHRM1
Ammonia Solution, Strong SCHEMBL1399858 0.78 TSHR (0.54) BCHECHRM2CHRM4CHRM5CHRM1
Hydrochloric Acid SCHEMBL130714 0.78 TSHR (0.54) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2420885-B1 Switchable imaging device using mesoporous particles DELTA ELECTRONICS INC (TW) 2013-09-18 EP disclosed
EP-2420885-A1 Switchable imaging device using mesoporous particles Delta Electronics, Inc. (TW) 2012-02-22 EP disclosed