Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 3/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342839 | 0.91 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6350295 | 0.89 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6341807 | 0.87 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6344918 | 0.87 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6341743 | 0.86 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6339452 | 0.86 | MEN1 (0.42) | MEN1KMT2APOLBCCR5CCR2 | |
| SCHEMBL5655925 | 0.85 | RARB (0.49) | MEN1KMT2ACCR5CCR2CCR3 | |
| SCHEMBL6351901 | 0.84 | CCR5 (0.33) | MEN1KMT2ACCR5CCR2HRH3 | |
| SCHEMBL6341045 | 0.80 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6342677 | 0.78 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1186604-A1 | BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |