Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 15/20 | 0.64 |
| ▸ | PGR | P06401 | 11/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676592 | 0.88 | NR3C1 (0.54) | NR3C1NR3C2PGR | |
| SCHEMBL1635103 | 0.86 | NR3C1 (0.77) | NR3C1NR3C2PGR | |
| SCHEMBL6640500 | 0.82 | NR3C1 (0.62) | NR3C1NR3C2PGR | |
| SCHEMBL1634715 | 0.79 | NR3C1 (0.68) | NR3C1NR3C2PGR | |
| SCHEMBL6639379 | 0.79 | NR3C1 (0.65) | NR3C1NR3C2PGR | |
| SCHEMBL291520 | 0.79 | NR3C1 (0.98) | NR3C1NR3C2PGR | |
| SCHEMBL676591 | 0.79 | NR3C1 (0.62) | NR3C1NR3C2PGR | |
| SCHEMBL292195 | 0.78 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL6353031 | 0.78 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL1634939 | 0.77 | NR3C1 (0.77) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903215-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-06-07 | — | — | US | disclosed |