⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27847423 | 1.00 | — | — | |
| Carbamic Acid SCHEMBL28262773 | 0.83 | ACHE (0.37) | — | |
| SCHEMBL13236563 | 0.72 | — | — | |
| SCHEMBL5514033 | 0.69 | — | — | |
| SCHEMBL726780 | 0.69 | — | — | |
| SCHEMBL16162693 | 0.69 | — | — | |
| SCHEMBL6361146 | 0.69 | — | — | |
| SCHEMBL7638172 | 0.69 | — | — | |
| SCHEMBL12656351 | 0.69 | — | — | |
| SCHEMBL14616103 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222093-A1 | Methods for restoring cognitive function following systemic stress | PEARLMAN RODNEY | 2005-10-06 | — | — | US | disclosed |
| EP-1372620-A2 | METHODS FOR RESTORING COGNITIVE FUNCTION FOLLOWING SYSTEMIC STRESS | Saegis Pharmaceuticals (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20020187977-A1 | Methods for restoring cognitive function following systemic stress | SAEGIS PHARMACEUTICALS, INC. | 2002-12-12 | — | — | US | disclosed |
| WO-2002074293-A2 | METHODS FOR RESTORING COGNITIVE FUNCTION FOLLOWING SYSTEMIC STRESS | SAEGIS PHARMACEUTICALS INC (US) | 2002-09-26 | — | — | WO | disclosed |
| US-5545631-A | GAMMA-AMINOBUTYRIC ACID ANTAGONIST; TREATS PETIT-MAL TYPE EPILEPSIES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0463560-B1 | New antiepileptic agents | CIBA GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |
| US-5424441-A | Nootropic, antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1995-06-13 | — | — | US | disclosed |
| US-5407922-A | GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| CN-1099801-A | Peptides | SANDOZ LTD (CH) | 1995-03-08 | — | — | CN | disclosed |
| EP-0402312-B1 | P-substituted propane-phosphinic acid compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5177251-A | Cytoprotective, antisecretory, side effect reduction | G. D. SEARLE & CO. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0463560-A1 | New antiepileptic agents | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |
| US-5064819-A | Antidepressants, anxiolytic agents, GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5051524-A | Treatment of a phosphinic acid with an anhydrous protic medium | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| US-5013863-A | Learning enhancement | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0402312-A2 | P-substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1990-12-12 | — | — | EP | disclosed |
| CN-1046892-A | FLUORINATED ARACHIDONIC ACID DERIVATIVES | MERRELL DOW PHARMA (US) | 1990-11-14 | — | — | CN | disclosed |
| EP-0319479-A2 | Substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319482-A2 | Novel substituted propane phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| CN-1032935-A | FLUORINATED ARACHIDONIC ACID DERIVATIVES | MERRELL DOW PHARMA (US) | 1989-05-17 | — | — | CN | disclosed |