Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | PTPRF | P10586 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628651 | 0.88 | CHRM2 (0.72) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL11597593 | 0.84 | CHRM2 (0.79) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL17187969 | 0.81 | CHRM2 (0.64) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL1041853 | 0.81 | MEN1 (0.69) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL1803792 | 0.81 | CHRM2 (0.64) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL22749543 | 0.80 | CHRM2 (0.58) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL6246420 | 0.80 | CHRM2 (0.58) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL10045277 | 0.79 | CHRM2 (0.90) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL3155876 | 0.79 | CYP1A2 (0.64) | CHRM2PTPRFPTPN2PTPN1PTPN11 | |
| Hydrochloric Acid SCHEMBL8365207 | 0.79 | CHRM2 (0.62) | CHRM2PTPRFPTPN2PTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | GPR119, GIPR, GCGR | CHRM2 3245/4885PTPRF 1482/4885PTPN2 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.