Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166389 | 0.80 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL6166962 | 0.79 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL6165798 | 0.78 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL6165790 | 0.78 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL6174173 | 0.76 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL6166200 | 0.76 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL6167691 | 0.74 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL6173620 | 0.74 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL6168813 | 0.73 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL6167109 | 0.73 | CRHR1 (0.50) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6964965-B2 | Substituted pyrazine derivatives | PHARMACIA & UPJOHN (US) | 2005-11-15 | — | — | US | claimed |