Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 5/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6353223 | 0.99 | EPHX2 (0.41) | EPHX2CYP2C9CYP2J2MAPTMAPK14 | |
| SCHEMBL6341778 | 0.88 | EPHX2 (0.42) | EPHX2CYP2C9CYP2J2MAPTMAPK14 | |
| Hydrochloric Acid SCHEMBL6344658 | 0.88 | EPHX2 (0.41) | EPHX2CYP2C9CYP2J2MAPTMAPK14 | |
| SCHEMBL6345731 | 0.86 | MAPK14 (0.41) | MAPK14KDM4EPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL6346836 | 0.86 | KDM4E (0.42) | EPHX2CYP2C9CYP2J2MAPTMAPK14 | |
| Hydrochloric Acid SCHEMBL6352351 | 0.86 | KDM4E (0.37) | EPHX2CYP2C9CYP2J2MAPTL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL6346762 | 0.84 | EPHX2 (0.42) | EPHX2CYP2C9CYP2J2MAPTMAPK14 | |
| Hydrochloric Acid SCHEMBL6355505 | 0.83 | MAPT (0.45) | EPHX2CYP2C9CYP2J2MAPTL3MBTL1 | |
| SCHEMBL4837480 | 0.82 | MAPK14 (0.45) | MAPTMAPK14KDM4EPOLBGHSR | |
| SCHEMBL6344241 | 0.82 | KDM4E (0.43) | MAPK14KDM4EPOLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878725-B2 | Serine protease inhibitors | ELI LILLY AND COMPANY (US) | 2005-04-12 | — | — | US | claimed |
| EP-1289950-B1 | SERINE PROTEASE INHIBITORS | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | claimed |
| US-20030078438-A1 | Serine protease inhibitors | ELI LILLY AND COMPANY | 2003-04-24 | — | — | US | claimed |
| US-6878725-B2 | Serine protease inhibitors | ELI LILLY AND COMPANY (US) | 2005-04-12 | — | — | US | disclosed |
| US-20040242656-A1 | Serine protease inhibitors | LIEBESCHUETZ JOHN WALTER (GB) | 2004-12-02 | — | — | US | disclosed |
| US-20030078438-A1 | Serine protease inhibitors | ELI LILLY AND COMPANY | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078438-A1 | Serine protease inhibitors | HPN, LPXN, PRSS1 | EPHX2 1259/4885CYP2C9 2462/4885CYP2J2 2186/4885 |
| US-20040242656-A1 | Serine protease inhibitors | SERPINE1, PRSS1, SERPINB1 | EPHX2 1576/4885CYP2C9 2235/4885CYP2J2 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.