Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318948 | 0.85 | TDP1 (0.43) | TDP1CYP2C9CYP2C19 | |
| SCHEMBL28208452 | 0.81 | TDP1 (0.42) | TDP1CYP2C9CYP2C19 | |
| SCHEMBL16752079 | 0.80 | TDP1 (0.42) | TDP1CYP2C9CYP2C19PRMT3CARM1 | |
| SCHEMBL18221733 | 0.77 | DNM1 (0.52) | TDP1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL13976195 | 0.77 | DNM1 (0.52) | TDP1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL20362314 | 0.74 | CA12 (0.38) | CYP2C9CYP2C19TSHR | |
| SCHEMBL11184192 | 0.74 | CA12 (0.38) | CYP2C9CYP2C19TSHR | |
| SCHEMBL20032065 | 0.74 | DNM1 (0.38) | TDP1CYP2C9CYP2C19PRMT3CARM1 | |
| SCHEMBL15558978 | 0.74 | DNM1 (0.48) | TDP1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL6137087 | 0.73 | TDP1 (0.44) | TDP1CYP2C9CYP2C19PRMT3CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090386-A1 | Catalyst blends for producing low thermal desorption polyurethane foams | WENDEL STEPHAN H (DE) | 2005-04-28 | — | — | US | claimed |