Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360933 | 0.95 | MEN1 (0.51) | KMT2AMEN1HTR1AADRA1DADRA1A | |
| SCHEMBL6354703 | 0.85 | ALDH1A1 (0.46) | SMPD1HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL6354708 | 0.85 | ALDH1A1 (0.46) | SMPD1HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL6354712 | 0.85 | MAPK1 (0.46) | SMPD1HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL21667915 | 0.83 | SMN1; SMN2 (0.47) | HDAC1HDAC8HDAC6KMT2AMEN1 | |
| SCHEMBL6351319 | 0.82 | PDE4B (0.59) | HDAC1HDAC6KMT2AMEN1PDE4A | |
| SCHEMBL28258075 | 0.80 | MAPK1 (0.44) | SMPD1HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL1465575 | 0.80 | SMPD1 (0.55) | SMPD1HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL13222774 | 0.80 | BCHE (0.51) | SMPD1HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL13017315 | 0.79 | SMPD1 (0.54) | SMPD1HDAC1HDAC8HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239841-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
| WO-2005051381-A1 | Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239841-A1 | New compounds | MCHR1, NPY1R, HCRTR1 | SMPD1 2296/4885HDAC1 1122/4885HDAC8 2117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.