Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPD | P32754 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29430691 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| SCHEMBL5961 | 0.98 | ALDH1A1 (0.58) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| Methyl Alcohol SCHEMBL28966984 | 0.93 | ALDH1A1 (0.53) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| SCHEMBL4638626 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| SCHEMBL19878494 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| SCHEMBL29739317 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| SCHEMBL29836953 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| SCHEMBL19878569 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| SCHEMBL113070 | 0.83 | TDP1 (0.60) | ALDH1A1HIF1ACYP3A4HPGDALOX15 | |
| SCHEMBL29580528 | 0.83 | TDP1 (0.60) | ALDH1A1HIF1ACYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282812-A1 | Inhibitors of cholesteryl ester transfer protein | ARRAY BIOPHARMA INC. | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282812-A1 | Inhibitors of cholesteryl ester transfer protein | CETP, LCAT, MTTP | ALDH1A1 2949/4885HIF1A 3002/4885CYP3A4 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.