Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28187696 | 0.98 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL2473231 | 0.98 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Sulfuric Acid SCHEMBL29013319 | 0.93 | TSHR (0.39) | TSHRHPGD | |
| Bromide SCHEMBL28358223 | 0.85 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL6392180 | 0.84 | TSHR (0.33) | TSHR | |
| Hydrochloric Acid SCHEMBL2399413 | 0.84 | TSHR (0.35) | TSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28703204 | 0.83 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3764876 | 0.82 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7039182 | 0.82 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Iodide SCHEMBL27893214 | 0.81 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467599-A | A kind of self-association type linked polymer coil and preparation method thereof | 中国海洋石油总公司 | 2017-03-01 | — | — | CN | disclosed |
| EP-1591462-A2 | Temperature-responsive polymer compound and process for producing the same | Amersham Biosciences KK (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-6956077-B1 | Temperature-responsive polymer compound and process for producing the same | AMERSHAM BIOSCIENCES KK (JP) | 2005-10-18 | — | — | US | disclosed |
| US-20050224415-A1 | Temperature-responsive polymer compound and process for producing the same | AMERSHAM BIOSCIENCES KK | 2005-10-13 | — | — | US | disclosed |
| EP-1153049-A1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | Amersham Pharmacia Biotech K.K. (JP) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000044800-A1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | AMERSHAM PHARMACIA BIOTECH K.K. (JP) | 2000-08-03 | — | — | WO | disclosed |