Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6355718 | 0.98 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| Bromide SCHEMBL28187696 | 0.96 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Sulfuric Acid SCHEMBL29013319 | 0.91 | TSHR (0.39) | TSHRHPGD | |
| Hydrochloric Acid SCHEMBL2399413 | 0.85 | TSHR (0.35) | TSHRHPGDALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28703204 | 0.85 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| Bromide SCHEMBL28358223 | 0.83 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Hydrochloric Acid SCHEMBL27662712 | 0.83 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL2733908 | 0.83 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6392180 | 0.83 | TSHR (0.33) | TSHR | |
| SCHEMBL3764876 | 0.81 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112029320-B | Ceramic powder capable of promoting blood circulation, sterilizing and releasing far infrared rays and application of ceramic powder in diatom ooze water-based paint | 刘鹏 | 2022-09-30 | — | — | CN | claimed |
| CN-114276488-B | Long-chain branch multi-head cationic polyacrylamide and application thereof | 河南博源新材料有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-111909069-B | Degradable quaternary ammonium salt compound and preparation method and application thereof | 安徽启威生物科技有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114276488-A | Long-chain branch multi-head cationic polyacrylamide and application thereof | 河南博源新材料有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-109439034-B | Bi-component diatom ooze water-based paint with zero VOC (volatile organic compounds) emission | 刘鹏 | 2021-05-14 | — | — | CN | claimed |
| CN-112029320-A | Ceramic powder capable of promoting blood circulation, sterilizing and releasing far infrared rays and application of ceramic powder in diatom ooze water-based paint | 刘鹏 | 2020-12-04 | — | — | CN | claimed |
| CN-105745188-B | High efficiency rheology modifiers with cationic components and uses thereof | 赫尔克里士公司 | 2019-09-10 | — | — | CN | claimed |
| CN-106467599-A | A kind of self-association type linked polymer coil and preparation method thereof | 中国海洋石油总公司 | 2017-03-01 | — | — | CN | claimed |
| EP-3055285-A2 | HIGH EFFICIENCY RHEOLOGY MODIFERS WITH CATIONIC COMPOMENTS AND USE THEREOF | Hercules Incorporated (US) | 2016-08-17 | — | — | EP | claimed |
| CN-105745188-A | High efficiency rheology modifiers with cationic components and uses thereof | 赫尔克里士公司 | 2016-07-06 | — | — | CN | claimed |
| CN-105085822-A | Sludge-proof type polycarboxylate water-reducer and normal temperature preparing method thereof | KEZHIJIE NEW MATERIALS GROUP CO LTD | 2015-11-25 | — | — | CN | claimed |
| WO-2015054069-A2 | HIGH EFFICIENCY RHEOLOGY MODIFERS WITH CATIONIC COMPOMENTS AND USE THEREOF | HERCULES INCORPORATED (US) | 2015-04-16 | — | — | WO | claimed |
| US-20150105500-A1 | HIGH EFFICIENCY RHEOLOGY MODIFERS WITH CATIONIC COMPONENTS AND USE THEREOF | AVOCA LLC | 2015-04-16 | — | — | US | claimed |
| CN-102304201-A | Hydrophobic association crosslinked polymer coil and preparation method thereof | CHINA NAT OFFSHORE OIL CORP | 2012-01-04 | — | — | CN | claimed |
| CN-102304200-A | Crosslinked polymer microspheres and preparation method thereof | CHINA NAT OFFSHORE OIL CORP | 2012-01-04 | — | — | CN | claimed |
| US-7901697-B2 | Synthetic thickeners for cosmetics | LAMBERTI SPA (IT) | 2011-03-08 | — | — | US | claimed |
| CN-117545826-B | Viscosity index improver, refrigerator oil, and working fluid composition for refrigerator | 三洋化成工业株式会社 | 2026-05-15 | — | — | CN | disclosed |
| US-12552889-B2 | Viscosity index improver, refrigerator oil, and working fluid composition for refrigerators | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2026-02-17 | — | — | US | disclosed |
| US-5336582-A | Electrophotographic image formation comprising an arylamine in a charge transport layer and an encapsulated toner | FUJI XEROX CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| US-5244768-A | Manufacturing process for an electrophotographic toner | FUJI XEROX CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552889-B2 | Viscosity index improver, refrigerator oil, and working fluid composition for refrigerators | F12, BCL2A1, C1R | TSHR 1422/4885HPGD 3587/4885ALDH1A1 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.