Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 11/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9881727 | 0.90 | ERN1 (0.51) | ERN1ALDH1A1KDM4ETRIM24TYR | |
| SCHEMBL4765815 | 0.84 | ERN1 (0.49) | ERN1ALDH1A1KDM4ERAB9ATRIM24 | |
| SCHEMBL6358014 | 0.83 | ALDH1A1 (0.43) | ERN1ALDH1A1KDM4ERAB9ATRIM24 | |
| SCHEMBL7601226 | 0.80 | APP (0.44) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL18641647 | 0.77 | ERN1 (0.47) | ERN1ALDH1A1KDM4ERAB9ATRIM24 | |
| SCHEMBL3612866 | 0.76 | ERN1 (0.44) | ERN1ALDH1A1KDM4EACACB | |
| SCHEMBL312237 | 0.75 | ALDH1A1 (0.53) | ERN1ALDH1A1RAB9ATRIM24TYR | |
| SCHEMBL30134856 | 0.75 | ALDH1A1 (0.53) | ERN1ALDH1A1RAB9ATRIM24TYR | |
| SCHEMBL4770355 | 0.74 | ALDH1A1 (0.53) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL20488634 | 0.74 | KDM4E (0.59) | ERN1ALDH1A1KDM4ERAB9ATRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |