Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Sucrose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.67 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sucrose SCHEMBL11571978 | 0.98 | CDK1 (0.67) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL10390145 | 0.91 | CDK1 (0.71) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL9619703 | 0.90 | CDK1 (0.70) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL31290281 | 0.88 | CDK1 (0.78) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL8693429 | 0.88 | CDK1 (0.78) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL23549940 | 0.88 | CDK1 (0.82) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL23690724 | 0.88 | CDK1 (0.82) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL25403456 | 0.88 | CDK1 (0.82) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL23690443 | 0.88 | CDK1 (0.82) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL21907913 | 0.88 | CDK1 (0.82) | CDK1CCNB1CA2CA9LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272692-A1 | Sucrose ester compounds useful as fungicides | FARONE WILLIAM A | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272692-A1 | Sucrose ester compounds useful as fungicides | ERG28, MGAM, CYP51A1 | CDK1 4340/4885CCNB1 4655/4885CA2 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.