SCHEMBL6358342

SCHEMBL6358342

Oc1ccc2c(Br)cccc2c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.46
ALOX15 P16050 3/20 0.42
HPGD P15428 2/20 0.42
RECQL P46063 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ADAMTS4 O75173 1/20 0.42
ALDH1A1 P00352 1/20 0.42
EGFR P00533 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
LMNA P02545 1/20 0.42
FYN P06241 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
CA6 P23280 1/20 0.42
CDK2 P24941 1/20 0.42
MMP12 P39900 1/20 0.42
ADAMTS5 Q9UNA0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5353432 0.82 IDO1 (0.40) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL31619445 0.79 IDO1 (0.48) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL11140356 0.78 TRPA1 (0.41) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL24373939 0.78 ESR1 (0.38) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL29163884 0.78 PARP1 (0.37) ALOX15HPGDHSD17B10TDP1ALDH1A1
SCHEMBL31037123 0.78 IDO1 (0.60) PTPN22ALOX15HPGDRECQLHSD17B10
SCHEMBL2994806 0.78 IDO1 (0.60) PTPN22ALOX15HPGDRECQLHSD17B10
SCHEMBL911866 0.78 IDO1 (0.52) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL30774147 0.78 IDO1 (0.52) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL1248415 0.77 PARP1 (0.50) HPGDHSD17B10ALDH1A1PARP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878659-B2 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2005-04-12 US disclosed
US-20040072681-A1 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2004-04-15 US disclosed
EP-1260524-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Titanium Co., Ltd. (JP) 2002-11-27 EP disclosed