Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 5/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913904 | 0.89 | KCNA3 (0.41) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2473766 | 0.86 | SMN1; SMN2 (0.44) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2470113 | 0.83 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2465586 | 0.83 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2918002 | 0.82 | SMN1; SMN2 (0.43) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2470303 | 0.80 | NPC1 (0.39) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2471492 | 0.80 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2469920 | 0.80 | GAA (0.41) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2472224 | 0.80 | NPC1 (0.37) | RAB9ASMN1; SMN2NPC1LMNAPKM | |
| SCHEMBL2467688 | 0.79 | KDM4E (0.44) | RAB9ASMN1; SMN2NPC1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171156-A1 | Prodrugs of potassium channel inhibitors | ICAGEN, INC. | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171156-A1 | Prodrugs of potassium channel inhibitors | KCNK5, KCNJ2, KCNA5 | RAB9A 3034/4885SMN1; SMN2 3547/4885NPC1 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.