Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | LDLR | P01130 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360783 | 0.86 | PPARA (0.51) | LMNAPPARAPPARG | |
| SCHEMBL6422826 | 0.84 | PPARA (0.53) | PPARAPPARG | |
| SCHEMBL6359776 | 0.83 | PPARA (0.46) | PPARAPPARGADORA3 | |
| SCHEMBL6362936 | 0.79 | PPARA (0.52) | PPARAPPARG | |
| SCHEMBL6364104 | 0.79 | PPARA (0.52) | PPARAPPARG | |
| SCHEMBL6357777 | 0.75 | PPARA (0.46) | PPARAPPARGADORA3 | |
| SCHEMBL7593129 | 0.72 | PPARA (0.43) | PPARAPPARGADORA3 | |
| SCHEMBL6363253 | 0.72 | PPARA (0.57) | PPARAPPARG | |
| SCHEMBL6544739 | 0.71 | PPARA (0.48) | PPARAPPARG | |
| SCHEMBL6363524 | 0.69 | PPARG (0.52) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075377-A1 | PPAR compounds | PFIZER INC | 2005-04-07 | — | — | US | disclosed |
| US-20020169192-A1 | PPAR compounds | HAYWARD CHERYL M (US) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169192-A1 | PPAR compounds | PPARA, PPARG, PPARD | NCOA1 28/4885NCOA3 44/4885GPR132 242/4885 |
| US-20050075377-A1 | PPAR compounds | PPARA, PPARG, PPARD | NCOA1 28/4885NCOA3 44/4885GPR132 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.