Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544746 | 0.83 | PPARG (0.43) | PPARAPPARGTBXAS1TDP1L3MBTL1 | |
| SCHEMBL6422826 | 0.82 | PPARA (0.53) | PPARAPPARGTBXAS1TDP1L3MBTL1 | |
| SCHEMBL6545724 | 0.79 | PPARA (0.49) | PPARAPPARGS1PR4S1PR1S1PR3 | |
| SCHEMBL6544732 | 0.76 | PPARG (0.43) | PPARAPPARGTBXAS1 | |
| SCHEMBL6364104 | 0.76 | PPARA (0.52) | PPARAPPARGCYP4F2CYP4A11TDP1 | |
| SCHEMBL6544734 | 0.74 | ADRB1 (0.46) | PPARAPPARG | |
| SCHEMBL6364312 | 0.72 | PPARG (0.58) | PPARAPPARG | |
| SCHEMBL6358985 | 0.71 | NCOA1 (0.40) | PPARAPPARG | |
| SCHEMBL6545721 | 0.68 | PPARA (0.46) | PPARAPPARGS1PR4S1PR1S1PR3 | |
| SCHEMBL6363253 | 0.68 | PPARA (0.57) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372632-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | Pfizer Products Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002064130-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2002-08-22 | — | — | WO | disclosed |