Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25900771 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL671957 | 0.79 | ELANE (0.49) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL18666368 | 0.76 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15008954 | 0.76 | MEN1 (0.47) | MEN1KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL6360678 | 0.76 | KMT2A (0.47) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL182108 | 0.76 | MEN1 (0.47) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL23612174 | 0.75 | KMT2A (0.43) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL11899706 | 0.75 | SMN1; SMN2 (0.50) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL14128469 | 0.75 | F2 (0.45) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL152495 | 0.75 | GAA (0.59) | MEN1KMT2APKMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050271584-A1 | Biphenyls and fluorenes as imaging agents in alzheimer's disease | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271584-A1 | Biphenyls and fluorenes as imaging agents in alzheimer's disease | APP, BACE2, BACE1 | MEN1 665/4885KMT2A 3164/4885PKM 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.