Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | DNMT1 | P26358 | 8/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447251 | 1.00 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL447250 | 1.00 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL447249 | 1.00 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL5982338 | 1.00 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9803687 | 0.91 | DNMT1 (0.57) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9803679 | 0.91 | DNMT1 (0.57) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL5982360 | 0.91 | DNMT1 (0.57) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9803693 | 0.91 | DNMT1 (0.57) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2293952 | 0.89 | DNMT1 (0.57) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL5982097 | 0.89 | DNMT1 (0.57) | TK1CYP1A2CYP3A4TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137764-B1 | NEW MEDICAL USE OF GENE AND VECTOR ENCODING A MULTISUBSTRATE DEOXYRIBONUCLEOSIDASE | ZGENE AS (DK) | 2005-03-02 | — | — | EP | disclosed |
| US-6582947-B1 | Nucleotide sequences coding enzymatic polypeptide for use in the virus treatment of cancer and viral infection | BIO VICI (CH) | 2003-06-24 | — | — | US | disclosed |
| EP-1137764-A1 | NEW MEDICAL USE OF GENE AND VECTOR ENCODING A MULTISUBSTRATE DEOXYRIBONUCLEOSIDASE | Biovici (CH) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000036099-A1 | NEW MEDICAL USE OF GENE AND VECTOR ENCODING A MULTISUBSTRATE DEOXYRIBONUCLEOSIDASE | BIOVICI (CH) | 2000-06-22 | — | — | WO | disclosed |