Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL6361889 | 1.00 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| Propene SCHEMBL6366659 | 1.00 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL169664 | 0.94 | THRB (0.58) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL16308965 | 0.92 | THRB (0.56) | THRBTSHRALDH1A1TP53HIF1A | |
| Ethylene SCHEMBL3377998 | 0.91 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| Phosphoric Acid SCHEMBL7070884 | 0.88 | THRB (0.51) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL17109944 | 0.87 | THRB (0.46) | THRBTSHRALDH1A1TDP1POLB | |
| Propene SCHEMBL19409471 | 0.86 | TSHR (0.44) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL16584654 | 0.85 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL16584784 | 0.85 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215756-A1 | Basic polymer obtained by hydrogenation | STOCKHAUSEN GMBH (DE) | 2005-09-29 | — | — | US | disclosed |
| US-4282128-A | ISOCYANATE REACTED WITH DIALKYLALKANOLAMINE AND HYDROXY ACRYLATE OR ALLYL ETHER, OPOXY-AMINE ADDUCT | VIANOVA KUNSTHARZ, A.G. (AT) | 1981-08-04 | — | — | US | disclosed |