SCHEMBL6360755

SCHEMBL6360755

N#Cc1ccc2[nH]c(-c3ccc(Cl)c(C(F)(F)F)c3)c(CCCC(=O)O)c2c1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 20/20 0.55
CYP2C9 P11712 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6361796 0.88 CXCR2 (0.55) CXCR2CYP2C9
SCHEMBL6359800 0.88 CXCR2 (0.57) CXCR2CYP2C9
SCHEMBL7241414 0.88 TSPO (0.43) CXCR2
SCHEMBL6362470 0.87 CXCR2 (0.55) CXCR2CYP2C9
SCHEMBL6365313 0.86 CXCR2 (0.57) CXCR2CYP2C9
SCHEMBL6362473 0.85 CXCR2 (0.55) CXCR2CYP2C9
SCHEMBL6364537 0.84 CXCR2 (0.59) CXCR2CYP2C9
SCHEMBL6364534 0.84 CXCR2 (0.63) CXCR2CYP2C9
SCHEMBL6361142 0.83 CXCR2 (0.52) CXCR2CYP2C9
SCHEMBL6362080 0.82 CXCR2 (0.59) CXCR2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050100902-A1 5-cyano-1h-indole derivatives as antagonist of the inerleukine-8 receptors LABORATORIES FOURNIER S.A. (FR) 2005-05-12 US disclosed