Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6362080 | 0.92 | CXCR2 (0.59) | CXCR2CYP2C9 | |
| SCHEMBL6359800 | 0.89 | CXCR2 (0.57) | CXCR2CYP2C9 | |
| SCHEMBL6365313 | 0.89 | CXCR2 (0.57) | CXCR2CYP2C9 | |
| SCHEMBL6362470 | 0.88 | CXCR2 (0.55) | CXCR2CYP2C9 | |
| SCHEMBL6362563 | 0.88 | CXCR2 (0.72) | CXCR2CYP2C9 | |
| SCHEMBL6364534 | 0.87 | CXCR2 (0.63) | CXCR2CYP2C9 | |
| SCHEMBL7240538 | 0.85 | TSPO (0.47) | CXCR2 | |
| SCHEMBL6364537 | 0.85 | CXCR2 (0.59) | CXCR2CYP2C9 | |
| SCHEMBL6361796 | 0.84 | CXCR2 (0.55) | CXCR2CYP2C9 | |
| SCHEMBL6362473 | 0.82 | CXCR2 (0.55) | CXCR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050100902-A1 | 5-cyano-1h-indole derivatives as antagonist of the inerleukine-8 receptors | LABORATORIES FOURNIER S.A. (FR) | 2005-05-12 | — | — | US | disclosed |