Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679777 | 0.95 | F10 (0.86) | F10 | |
| SCHEMBL4679815 | 0.93 | F10 (0.85) | F10 | |
| SCHEMBL6359965 | 0.89 | F10 (0.69) | F10 | |
| SCHEMBL6362334 | 0.87 | F10 (1.00) | F10 | |
| SCHEMBL6362350 | 0.86 | F10 (0.79) | F10 | |
| SCHEMBL6365232 | 0.86 | F10 (1.00) | F10 | |
| SCHEMBL6363074 | 0.86 | F10 (0.77) | F10 | |
| SCHEMBL6362528 | 0.86 | F10 (1.00) | F10 | |
| SCHEMBL6367612 | 0.85 | F10 (0.82) | F10 | |
| SCHEMBL6613889 | 0.84 | F10 (0.72) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100364971-C | Pyrrolidin-2-ones as factor Xa inhibitors | GLAXO GROUP LTD (GB) | 2008-01-30 | — | — | CN | disclosed |
| CN-1620434-A | Pyrrolidine-2-ones as factor Xa inhibitors | GLAXO GROUP LTD (GB) | 2005-05-25 | — | — | CN | disclosed |
| US-20050059726-A1 | Pyrrolidine-2-ones as factor xa inhibitors | GLAXO GROUP LIMITED (GB) | 2005-03-17 | — | — | US | disclosed |
| EP-1456172-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053925-A1 | PYRROLIDINE-2-ONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059726-A1 | Pyrrolidine-2-ones as factor xa inhibitors | TFPI, F2, SERPINC1 | F10 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.