⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436856 | 0.81 | — | — | |
| SCHEMBL958545 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL4780449 | 0.78 | RAB9A (0.60) | — | |
| SCHEMBL4873752 | 0.76 | RAB9A (0.54) | — | |
| SCHEMBL4400464 | 0.76 | MAPT (0.53) | — | |
| SCHEMBL13900769 | 0.75 | RAB9A (0.53) | — | |
| SCHEMBL6449567 | 0.75 | MAPT (0.51) | — | |
| SCHEMBL19080596 | 0.75 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL28682965 | 0.75 | RAB9A (0.53) | — | |
| SCHEMBL14972833 | 0.75 | MAPT (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245498-A1 | Sterically-awkward beta-lactamase inhibitors | NORTHWESTERN UNIVERSITY | 2005-11-03 | — | — | US | claimed |
| US-6124297-A | COMBATTING INSECTS OR MITES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-26 | — | — | US | claimed |
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | claimed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | claimed |
| EP-0529680-B1 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-05-13 | — | — | EP | claimed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | claimed |
| EP-0548338-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES. | ANTIBIOTICOS SPA (IT) | 1993-06-30 | — | — | EP | claimed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | claimed |
| WO-1993002085-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS S.P.A. (IT) | 1993-02-04 | — | — | WO | claimed |
| US-20050245498-A1 | Sterically-awkward beta-lactamase inhibitors | NORTHWESTERN UNIVERSITY | 2005-11-03 | — | — | US | disclosed |
| WO-2004037163-A2 | STERICALLY-AWKWARD β-LACTAMASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2004-05-06 | — | — | WO | disclosed |
| US-20030236243-A1 | Sterically-awkward beta-lactamase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-25 | — | — | US | disclosed |
| US-6407248-B1 | INSECTICIDES, MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6124297-A | COMBATTING INSECTS OR MITES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0496106-A1 | Stable agrochemical compositions | Takeda Chemical Industries, Ltd. (JP) | 1992-07-29 | — | — | EP | disclosed |
| EP-0366189-A2 | Novel antimicrobial lactam-quinolones | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4399132-A | BACTERICIDES | AMERICAN CYANAMID COMPANY (US) | 1983-08-16 | — | — | US | disclosed |