SCHEMBL6364133

SCHEMBL6364133

CCCCCCCC(=O)CCC(C)C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.59
MAPT P10636 1/20 0.59
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
LMNA P02545 2/20 0.48
MEN1 O00255 2/20 0.48
FAAH O00519 1/20 0.48
MAPK1 P28482 1/20 0.48
HAO1 Q9UJM8 1/20 0.48
PPARG P37231 6/20 0.48
PPARD Q03181 6/20 0.48
PPARA Q07869 6/20 0.48
HDAC11 Q96DB2 5/20 0.48
TSHR P16473 4/20 0.48
GPR84 Q9NQS5 4/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
PTPN1 P18031 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8896603 1.00 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA
SCHEMBL22443732 1.00 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA
SCHEMBL9327687 1.00 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA
SCHEMBL6859048 1.00 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA
SCHEMBL1966054 0.98 KMT2A (0.56) KMT2AMAPTCES2CES1LMNA
SCHEMBL8896878 0.91 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA
SCHEMBL8898488 0.91 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA
SCHEMBL8897363 0.91 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA
SCHEMBL15401153 0.91 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA
SCHEMBL8899009 0.91 KMT2A (0.59) KMT2AMAPTCES2CES1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115259733-A Cement admixture and production process thereof 浙江长盈建材科技有限公司 2022-11-01 CN claimed
CN-112679137-A Concrete additive for highway 江西富创新材料有限公司 2021-04-20 CN claimed
CN-116425449-B Mortar additive and application thereof 青岛智成华建筑材料有限公司 2024-08-30 CN disclosed
CN-116425449-A Mortar additive and application thereof 青岛智成华建筑材料有限公司 2023-07-14 CN disclosed
CN-116115678-A Chinese medicinal preparation for treating acne and its preparation method 天津市武清区爱康中医医院 2023-05-16 CN disclosed
CN-115259733-A Cement admixture and production process thereof 浙江长盈建材科技有限公司 2022-11-01 CN disclosed
CN-115259733-A Cement admixture and production process thereof 浙江长盈建材科技有限公司 2022-11-01 CN disclosed
CN-113831052-B Special additive for assembled mortar products 河北恒誉伟业建材有限公司 2022-03-18 CN disclosed
CN-113831052-A Special additive for assembled mortar products 北京恒誉伟业建材有限公司 2021-12-24 CN disclosed
CN-112679137-A Concrete additive for highway 江西富创新材料有限公司 2021-04-20 CN disclosed
CN-110937843-A Preparation process of concrete composite additive 龚小琴 2020-03-31 CN disclosed
CN-103585452-A Traditional Chinese medicinal composition for treating xerophthalmia XIE LIKE 2014-02-19 CN disclosed
CN-103505535-A Medicine used for treating psoriasis as well as extraction method, extract and application thereof UNIV PEKING FOUNDER GROUP CO 2014-01-15 CN disclosed
CN-102599337-B Traditional Chinese medicinal composition for increasing feed intake and feed conversion rate of livestock and poultry and preparation method, preparation and feed thereof GUO YAOTING 2013-09-18 CN disclosed
US-20130131106-A1 BIFUNCTIONAL RHO KINASE INHIBITOR COMPOUNDS, COMPOSITION AND USE INSPIRE PHARMACEUTICALS, INC. (US) 2013-05-23 US disclosed
CN-102599337-A Traditional Chinese medicinal composition for increasing feed intake and feed conversion rate of livestock and poultry and preparation method, preparation and feed thereof YAOTING GUO 2012-07-25 CN disclosed
WO-2012012282-A1 BIFUNCTIONAL RHO KINASE INHIBITOR COMPOUNDS, COMPOSITION AND USE INSPIRE PHARMACEUTICALS, INC. (US) 2012-01-26 WO disclosed
US-20050181080-A1 Chinese traditional medicines for psoriasis HUANG HSU-SHAN (TW) 2005-08-18 US disclosed
US-20030165533-A1 Chinese traditional medicines for psoriasis HUANG HSU-SHAN (TW) 2003-09-04 US disclosed
US-20030152588-A1 Chinese traditional medicines for psoriasis HUANG HSU-SHAN (TW) 2003-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131106-A1 BIFUNCTIONAL RHO KINASE INHIBITOR COMPOUNDS, COMPOSITION AND USE ROCK2, ROCK1, RHOA KMT2A 2348/4885MAPT 286/4885CES2 4768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.