Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 15/20 | 0.43 |
| ▸ | APOB | P04114 | 3/20 | 0.43 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.41 |
| ▸ | MICA | Q29983 | 2/20 | 0.41 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726262 | 0.86 | MTTP (0.43) | MTTPKLRK1MICARAET1L | |
| Granotapide SCHEMBL1484041 | 0.84 | MTTP (0.44) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL3727523 | 0.83 | MTTP (0.41) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL3731267 | 0.82 | MTTP (0.46) | MTTPAPOBMAPT | |
| SCHEMBL3730636 | 0.82 | KLRK1 (0.40) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL3726067 | 0.82 | KLRK1 (0.39) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL3728924 | 0.82 | PPARG (0.49) | MTTPAPOB | |
| SCHEMBL3731067 | 0.81 | KLRK1 (0.38) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5069233 | 0.81 | MTTP (0.44) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL3730846 | 0.81 | MTTP (0.46) | MTTPAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075367-A1 | Ester compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075367-A1 | Ester compound and medicinal use thereof | LIPC, CES1, MTTP | MTTP 3/4885APOB 39/4885KLRK1 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.