⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL921849 | 0.70 | XDH (0.53) | — | |
| SCHEMBL5846316 | 0.66 | MAPT (0.40) | — | |
| SCHEMBL207585 | 0.62 | — | — | |
| SCHEMBL5041003 | 0.59 | — | — | |
| SCHEMBL5039703 | 0.59 | — | — | |
| SCHEMBL5036394 | 0.59 | — | — | |
| SCHEMBL16878358 | 0.57 | — | — | |
| SCHEMBL16878384 | 0.57 | — | — | |
| SCHEMBL218085 | 0.57 | — | — | |
| SCHEMBL17265838 | 0.57 | DYRK1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271949-A1 | GLP-1R MODULATING COMPOUNDS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| WO-2023164358-A1 | GLP-1R MODULATING COMPOUNDS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-08-31 | — | — | WO | disclosed |
| US-20230271949-A1 | GLP-1R MODULATING COMPOUNDS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| CN-116209652-A | Synthesis of pyrrole acid derivatives | 英菲克斯治疗有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20160326157-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-10 | — | — | US | disclosed |
| WO-2015103583-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-07-09 | — | — | WO | disclosed |
| US-6902879-B2 | Silver halide photographic emulsion, silver halide photosensitive material, and novel iridium complex and preparation process thereof | FUJI PHOTO FILM CO., LTD. (JP) | 2005-06-07 | — | — | US | disclosed |
| US-20040002025-A1 | Silver halide photographic emulsion, silver halide photosensitive material, and novel iridium complex and preparation process thereof | FUJI PHOTO FILM CO., LTD. | 2004-01-01 | — | — | US | disclosed |